Important Information about PROTONIX
Read more below.

Of course you want relief from your acid reflux symptoms. But what about the damage in your esophagus that erosive acid reflux disease causes?

With PROTONIX, you can actually treat both the symptoms and the damage of erosive acid reflux disease. It works like this. PROTONIX 40 mg shuts down many of the acid-producing pumps in the stomach to reduce the level of acid. So the erosions that may have developed in your esophagus will have time to heal.

Healing occurs in time.

While your symptoms may subside quickly, actual healing may take a bit longer. In a clinical study, PROTONIX 40 mg has been shown to heal more than 9 out of 10 patients with erosive acid reflux disease after 8 weeks of starting treatment.^1,2 To maintain healing, doctors may prescribe PROTONIX beyond 8 weeks. Individual results may vary.

So follow your doctor's instructions and give the healing a little time. Be sure to take PROTONIX for as long as your doctor prescribes. Once you've completed your treatment, monitor how you feel and speak to your doctor if your acid reflux symptoms return.

¹ Data on file, Wyeth Pharmaceuticals Inc.

² PROTONIX® (pantoprazole sodium) Prescribing Information, Wyeth Pharmaceuticals Inc.

Important Product and Safety Information

Indications

PROTONIX is a prescription drug that is used to treat and maintain healing of erosive acid reflux disease, also known as erosive GERD (breaks in the lining of the esophagus), and relieve associated symptoms that may include frequent and persistent heartburn and stomach acid backup. Most patients heal within 8 weeks of treatment. Doctors may prescribe PROTONIX beyond 8 weeks to maintain healing or to prevent a recurrence of your symptoms. Controlled studies did not extend beyond 12 months.

Important Safety Information

In clinical trials, the most frequently reported side effects with PROTONIX Delayed-Release Tablets were headache, diarrhea, and gas. Relief of your symptoms while on PROTONIX does not exclude the possibility that serious stomach conditions are present. Patients who are allergic to any ingredient of PROTONIX should not take it.

Please see Important Prescribing Information.