Important Information about PROTONIX
Read more below.

A few simple things to keep in mind:

• • To get the most out of PROTONIX, follow your doctor's instructions.
• • Swallow tablets whole, with or without food in the stomach. Do not chew or crush them.
• • PROTONIX can be taken with antacids and many other medications. But be sure to tell your doctor if you're taking other medicines.

So how long should you take PROTONIX?

That's for your doctor to decide. With PROTONIX, you may find relief from your symptoms quickly. But damage to your esophagus may need more time to heal.

It helps to understand how PROTONIX heals. And it's important to keep taking it for as long as your doctor recommends. As always, talk with your doctor or pharmacist if you have any questions about your medication.

Important Product and Safety Information

Indications

PROTONIX is a prescription drug that is used to treat and maintain healing of erosive acid reflux disease, also known as erosive GERD (breaks in the lining of the esophagus), and relieve associated symptoms that may include frequent and persistent heartburn and stomach acid backup. Most patients heal within 8 weeks of treatment. Doctors may prescribe PROTONIX beyond 8 weeks to maintain healing or to prevent a recurrence of your symptoms. Controlled studies did not extend beyond 12 months.

Important Safety Information

In clinical trials, the most frequently reported side effects with PROTONIX Delayed-Release Tablets were headache, diarrhea, and gas. Relief of your symptoms while on PROTONIX does not exclude the possibility that serious stomach conditions are present. Patients who are allergic to any ingredient of PROTONIX should not take it.

Please see Important Prescribing Information.